Purified Anti-Mouse CD31 Antibody[MEC13.3], Functional Grade (AN009430)
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For research use only.
| Alternate Names | Adhesion molecule, CD31 antigen, CD31 EndoCAM, CD31/EndoCAM, cluster of differentiation 31, endoCAM, FLJ34100, FLJ58394, GPIIA, GPIIA', PECA1, Pecam 1, PECAM 1 CD31 EndoCAM, platelet and endothelial cell adhesion molecule 1, Platelet/endothelial cell adhesion molecule 1, CD31, Platelet endothelial cell adhesion molecule, Pecam, Pecam-1, Pecam1, endocam, gpIIa |
| Clone | |
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume;Block Reported in the literature |
| Background | CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Mouse CD31 protein |
| Abbre | CD31 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3], Functional Grade |
| Applications |
FCM;Block
|
| Cellular Localization |
Cell membrane
|
| Concentration |
≥ 3 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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